Biblioteca Humberto Rosselli Quijano
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Añadir el resultado a su cestaPsychedelic Therapeutics for Adolescents: Ethics, Safety, Opportunities, and Equipoise en Journal of the American Academy of Child & Adolescent Psychiatry, Año 2025 - Vol. 64 - No. 7 (July)
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[artículo]
Título : Psychedelic Therapeutics for Adolescents: Ethics, Safety, Opportunities, and Equipoise Tipo de documento: texto impreso Fecha de publicación: 2026 Artículo en la página: 755-756 Idioma : Inglés (eng) Idioma original : Inglés (eng) Etiquetas: Alucinógenos efectos adversos, Alucinógenos uso terapéutico, Equilibrio terapéutico, Seres humanos, Adolescentes. Resumen: We read with interest the Commentary by Jeffrey et al. encouraging clinical research using psychedelics for adolescents.1 Throughout their commentary, the authors operate under the general presupposition that psychedelics have demonstrated a favorable safety profile in adults, and that therefore teenagers approaching an adult level of neurodevelopment can likely be safely treated with appropriate safeguards. Although we concur that there is an urgent need for new psychopharmaceuticals for adolescents, we question this assumption of safety, given increasing evidence of risks associated with psychedelics in adult trials.2,3.
(Copyright © 2024 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.)En línea: https://doi.org/10.1016/j.jaac.2024.12.001 Link: ./index.php?lvl=notice_display&id=31636
in Journal of the American Academy of Child & Adolescent Psychiatry > Año 2025 - Vol. 64 - No. 7 (July) . - 755-756[artículo] Psychedelic Therapeutics for Adolescents: Ethics, Safety, Opportunities, and Equipoise [texto impreso] . - 2026 . - 755-756.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of the American Academy of Child & Adolescent Psychiatry > Año 2025 - Vol. 64 - No. 7 (July) . - 755-756
Etiquetas: Alucinógenos efectos adversos, Alucinógenos uso terapéutico, Equilibrio terapéutico, Seres humanos, Adolescentes. Resumen: We read with interest the Commentary by Jeffrey et al. encouraging clinical research using psychedelics for adolescents.1 Throughout their commentary, the authors operate under the general presupposition that psychedelics have demonstrated a favorable safety profile in adults, and that therefore teenagers approaching an adult level of neurodevelopment can likely be safely treated with appropriate safeguards. Although we concur that there is an urgent need for new psychopharmaceuticals for adolescents, we question this assumption of safety, given increasing evidence of risks associated with psychedelics in adult trials.2,3.
(Copyright © 2024 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.)En línea: https://doi.org/10.1016/j.jaac.2024.12.001 Link: ./index.php?lvl=notice_display&id=31636 What About Life Skills? Tailoring Interventions for Autism and Beyond en Journal of the American Academy of Child & Adolescent Psychiatry, Año 2025 - Vol. 64 - No. 7 (July)
[artículo]
Título : What About Life Skills? Tailoring Interventions for Autism and Beyond Tipo de documento: texto impreso Fecha de publicación: 2026 Artículo en la página: pp. 761-764 Idioma : Inglés (eng) Idioma original : Inglés (eng) Etiquetas: Actividades de la vida diaria, Trastorno del espectro autista (psicología), Trastorno del espectro autista (terapia niño),
Niño)Resumen: Nearly 50 years of research have carefully documented daily living skills (DLS) deficits in individuals with autism spectrum disorder, which emerge early in life, appear to persist across development, and seem to affect people across this very heterogeneous condition.1 The terminology and measures used to quantify life skills challenges vary across conditions, but such deficits are also common in people with intellectual disability, attention-deficit/hyperactivity disorder, internalizing and externalizing disorders, and schizophrenia and related psychotic disorders.2 Though deficits in life skills are not a diagnostic criterion for autism, they should be a focus of support and treatment across the life span.
(Copyright © 2025 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.)Link: ./index.php?lvl=notice_display&id=31638
in Journal of the American Academy of Child & Adolescent Psychiatry > Año 2025 - Vol. 64 - No. 7 (July) . - pp. 761-764[artículo] What About Life Skills? Tailoring Interventions for Autism and Beyond [texto impreso] . - 2026 . - pp. 761-764.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of the American Academy of Child & Adolescent Psychiatry > Año 2025 - Vol. 64 - No. 7 (July) . - pp. 761-764
Etiquetas: Actividades de la vida diaria, Trastorno del espectro autista (psicología), Trastorno del espectro autista (terapia niño),
Niño)Resumen: Nearly 50 years of research have carefully documented daily living skills (DLS) deficits in individuals with autism spectrum disorder, which emerge early in life, appear to persist across development, and seem to affect people across this very heterogeneous condition.1 The terminology and measures used to quantify life skills challenges vary across conditions, but such deficits are also common in people with intellectual disability, attention-deficit/hyperactivity disorder, internalizing and externalizing disorders, and schizophrenia and related psychotic disorders.2 Though deficits in life skills are not a diagnostic criterion for autism, they should be a focus of support and treatment across the life span.
(Copyright © 2025 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.)Link: ./index.php?lvl=notice_display&id=31638 Embodying AACAP's Presidential Initiative to Combat Digital Racism in Youth. en Journal of the American Academy of Child & Adolescent Psychiatry, Año 2025 - Vol. 64 - No. 7 (July)
[artículo]
Título : Embodying AACAP's Presidential Initiative to Combat Digital Racism in Youth. Tipo de documento: texto impreso Fecha de publicación: 2026 Artículo en la página: pp. 765-767 Idioma : Inglés (eng) Idioma original : Inglés (eng) Etiquetas: Racismo -- prevención y control, Psiquiatría infantil, Psiquiatría adolescente, Redes sociales, Sociedades médicas Link: ./index.php?lvl=notice_display&id=31639
in Journal of the American Academy of Child & Adolescent Psychiatry > Año 2025 - Vol. 64 - No. 7 (July) . - pp. 765-767[artículo] Embodying AACAP's Presidential Initiative to Combat Digital Racism in Youth. [texto impreso] . - 2026 . - pp. 765-767.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of the American Academy of Child & Adolescent Psychiatry > Año 2025 - Vol. 64 - No. 7 (July) . - pp. 765-767
Etiquetas: Racismo -- prevención y control, Psiquiatría infantil, Psiquiatría adolescente, Redes sociales, Sociedades médicas Link: ./index.php?lvl=notice_display&id=31639 Editorial: Meta-Analysis of Individual Participant Data From Trials of Selective Serotonin Reuptake Inhibitors for Pediatric Obsessive-Compulsive Disorder: A Gold Standard Approach. en Journal of the American Academy of Child & Adolescent Psychiatry, Año 2025 - Vol. 64 - No. 7 (July)
[artículo]
Título : Editorial: Meta-Analysis of Individual Participant Data From Trials of Selective Serotonin Reuptake Inhibitors for Pediatric Obsessive-Compulsive Disorder: A Gold Standard Approach. Tipo de documento: texto impreso Fecha de publicación: 2026 Artículo en la página: pp. 768-769 Idioma : Inglés (eng) Idioma original : Inglés (eng) Etiquetas: Trastorno obsesivo-compulsivo -- tratamiento farmacológico, Inhibidores selectivos de la recaptación de serotonina -- uso terapéutico, Metaanálisis como tema -- Adolescentes, Resumen: Pediatric obsessive-compulsive disorder (OCD) is a common (2% prevalence) and potentially debilitating condition.1 Early identification and intervention are critical because they may improve outcomes for children and adolescents with OCD and prevent long-term morbidity. The individual participant data (IPD) meta-analysis by Cohen and colleagues2 explores the efficacy of short-term trials of selective serotonin reuptake inhibitors (SSRIs) compared to placebo for treating children and adolescents with OCD. It also investigates the moderating effects of baseline patient variables on treatment outcome. Link: ./index.php?lvl=notice_display&id=31640
in Journal of the American Academy of Child & Adolescent Psychiatry > Año 2025 - Vol. 64 - No. 7 (July) . - pp. 768-769[artículo] Editorial: Meta-Analysis of Individual Participant Data From Trials of Selective Serotonin Reuptake Inhibitors for Pediatric Obsessive-Compulsive Disorder: A Gold Standard Approach. [texto impreso] . - 2026 . - pp. 768-769.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of the American Academy of Child & Adolescent Psychiatry > Año 2025 - Vol. 64 - No. 7 (July) . - pp. 768-769
Etiquetas: Trastorno obsesivo-compulsivo -- tratamiento farmacológico, Inhibidores selectivos de la recaptación de serotonina -- uso terapéutico, Metaanálisis como tema -- Adolescentes, Resumen: Pediatric obsessive-compulsive disorder (OCD) is a common (2% prevalence) and potentially debilitating condition.1 Early identification and intervention are critical because they may improve outcomes for children and adolescents with OCD and prevent long-term morbidity. The individual participant data (IPD) meta-analysis by Cohen and colleagues2 explores the efficacy of short-term trials of selective serotonin reuptake inhibitors (SSRIs) compared to placebo for treating children and adolescents with OCD. It also investigates the moderating effects of baseline patient variables on treatment outcome. Link: ./index.php?lvl=notice_display&id=31640 Editorial: Cross-Cultural Assessment: Concepts, Methods, and Application en Journal of the American Academy of Child & Adolescent Psychiatry, Año 2025 - Vol. 64 - No. 7 (July)
[artículo]
Título : Editorial: Cross-Cultural Assessment: Concepts, Methods, and Application Tipo de documento: texto impreso Fecha de publicación: 2026 Artículo en la página: PP 770-771 Idioma : Inglés (eng) Idioma original : Inglés (eng) Resumen: The author has reported no funding for this work.
Disclosure: Andres J. Pumariega has received royalties and licenses from Oxford Press. He is the Executive Committee and DEI Committee Chair of the American Association of Directors of Child and Adolescent Psychiatry (AADCAP). He is a grant recipient from the Florida Department of Health, UF Behavioral Health Collaborative Hubs for North Central Florida and Panhandle regions.
All statements expressed in this column are those of the authors and do not reflect the opinions of the Journal of the American Academy of Child and Adolescent Psychiatry. See the Guide for Authors for information about the preparation and submission of Editorials.Link: ./index.php?lvl=notice_display&id=31641
in Journal of the American Academy of Child & Adolescent Psychiatry > Año 2025 - Vol. 64 - No. 7 (July) . - PP 770-771[artículo] Editorial: Cross-Cultural Assessment: Concepts, Methods, and Application [texto impreso] . - 2026 . - PP 770-771.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of the American Academy of Child & Adolescent Psychiatry > Año 2025 - Vol. 64 - No. 7 (July) . - PP 770-771
Resumen: The author has reported no funding for this work.
Disclosure: Andres J. Pumariega has received royalties and licenses from Oxford Press. He is the Executive Committee and DEI Committee Chair of the American Association of Directors of Child and Adolescent Psychiatry (AADCAP). He is a grant recipient from the Florida Department of Health, UF Behavioral Health Collaborative Hubs for North Central Florida and Panhandle regions.
All statements expressed in this column are those of the authors and do not reflect the opinions of the Journal of the American Academy of Child and Adolescent Psychiatry. See the Guide for Authors for information about the preparation and submission of Editorials.Link: ./index.php?lvl=notice_display&id=31641 Editorial: The Future of Safety Signal Learning as a Biomarker of Risk and Treatment Target for Trauma-Related Psychopathology in Youth en Journal of the American Academy of Child & Adolescent Psychiatry, Año 2025 - Vol. 64 - No. 7 (July)
[artículo]
Título : Editorial: The Future of Safety Signal Learning as a Biomarker of Risk and Treatment Target for Trauma-Related Psychopathology in Youth Tipo de documento: texto impreso Fecha de publicación: 2026 Artículo en la página: pp. 772-774 Idioma : Inglés (eng) Idioma original : Inglés (eng) Etiquetas: Trastornos por estrés postraumático -- terapia, Trastornos por estrés postraumático -- fisiopatología, Trauma psicológico -- fisiopatología, Trauma psicológico -- terapia Resumen: More than two-thirds of youth will experience at least 1 traumatic event.1 Ongoing conflicts and increasingly pervasive natural disasters attributable to climate change signal that this number is on the rise.2,3 There is a significant need for trauma-informed interventions to mitigate the severity, chronicity, and cost of the physical and mental health effects of trauma (eg, cardiometabolic diseases, posttraumatic stress, anxiety, and depression). While such evidence-based interventions do exist, a significant proportion of youth do not respond to treatments such as cognitive-behavioral therapy, and globally an even larger proportion are unable to access treatment.4 Thus, there is a great need to identify and optimize new and existing trauma-informed treatment strategies through mechanism-focused research. In this issue, Kribakaran et al.5 explored safety signal learning and its neural underpinnings in 102 youths (ages 9-19; 46 girls), approximately half (n = 52) of whom were exposed to interpersonal trauma. They identified age- and exposure-related differences in brain regions and circuits related to threat detection (eg, centromedial amygdala), context processing (eg, anterior hippocampus), and regulation (eg, subgenual anterior cingulate cortex), with implications for risk of posttraumatic stress disorder and treatment across developmental stages. The findings push the needle forward regarding our understanding of the neurobiological underpinnings of aberrant learning processes in youth exposed to trauma and generate new questions regarding individual differences attributable to structural factors such as racism, as well as developmental questions requiring longitudinal testing. Link: ./index.php?lvl=notice_display&id=31642
in Journal of the American Academy of Child & Adolescent Psychiatry > Año 2025 - Vol. 64 - No. 7 (July) . - pp. 772-774[artículo] Editorial: The Future of Safety Signal Learning as a Biomarker of Risk and Treatment Target for Trauma-Related Psychopathology in Youth [texto impreso] . - 2026 . - pp. 772-774.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of the American Academy of Child & Adolescent Psychiatry > Año 2025 - Vol. 64 - No. 7 (July) . - pp. 772-774
Etiquetas: Trastornos por estrés postraumático -- terapia, Trastornos por estrés postraumático -- fisiopatología, Trauma psicológico -- fisiopatología, Trauma psicológico -- terapia Resumen: More than two-thirds of youth will experience at least 1 traumatic event.1 Ongoing conflicts and increasingly pervasive natural disasters attributable to climate change signal that this number is on the rise.2,3 There is a significant need for trauma-informed interventions to mitigate the severity, chronicity, and cost of the physical and mental health effects of trauma (eg, cardiometabolic diseases, posttraumatic stress, anxiety, and depression). While such evidence-based interventions do exist, a significant proportion of youth do not respond to treatments such as cognitive-behavioral therapy, and globally an even larger proportion are unable to access treatment.4 Thus, there is a great need to identify and optimize new and existing trauma-informed treatment strategies through mechanism-focused research. In this issue, Kribakaran et al.5 explored safety signal learning and its neural underpinnings in 102 youths (ages 9-19; 46 girls), approximately half (n = 52) of whom were exposed to interpersonal trauma. They identified age- and exposure-related differences in brain regions and circuits related to threat detection (eg, centromedial amygdala), context processing (eg, anterior hippocampus), and regulation (eg, subgenual anterior cingulate cortex), with implications for risk of posttraumatic stress disorder and treatment across developmental stages. The findings push the needle forward regarding our understanding of the neurobiological underpinnings of aberrant learning processes in youth exposed to trauma and generate new questions regarding individual differences attributable to structural factors such as racism, as well as developmental questions requiring longitudinal testing. Link: ./index.php?lvl=notice_display&id=31642 Systematic Review and Meta-Analysis of Individual Participant Data: Randomized, Placebo-Controlled Trials of Selective Serotonin Reuptake Inhibitors for Pediatric Obsessive-Compulsive Disorder en Journal of the American Academy of Child & Adolescent Psychiatry, Año 2025 - Vol. 64 - No. 7 (July)
[artículo]
Título : Systematic Review and Meta-Analysis of Individual Participant Data: Randomized, Placebo-Controlled Trials of Selective Serotonin Reuptake Inhibitors for Pediatric Obsessive-Compulsive Disorder Tipo de documento: texto impreso Fecha de publicación: 2026 Artículo en la página: pp 775-785 Idioma : Inglés (eng) Idioma original : Inglés (eng) Etiquetas: metaanálisis de datos de participantes individuales, trastorno obsesivo-compulsivo infantil, ensayos controlados aleatorios, ISRS Resumen: Objective Selective serotonin reuptake inhibitors (SSRIs) are the first choice in pharmacotherapy for children and adolescents with obsessive-compulsive disorder (OCD). SSRI trials for pediatric OCD have not been investigated using individual participant data (IPD), which is crucial for detecting patient-level effect modifiers. This study performed an IPD meta-analysis of efficacy of SSRIs compared with placebo and a meta-regression on baseline patient characteristics that might modify efficacy.Method Crude participant data from short-term, randomized, placebo-controlled SSRI trials for pediatric OCD were obtained from the registry of the Dutch regulatory authority. A systematic literature search was also performed, and authors were approached to provide IPD. A 1- and 2-stage analysis was conducted, with change on Children’s Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) as the primary outcome. Odds ratio (OR) with ≥35% CY-BOCS reduction was used as the responder outcome measure. Modifying effect of age, sex, weight, duration of illness, family history, and baseline symptom severity was examined. The Cochrane RoB 2.0 tool was used to examine methodological rigor, and Grading of Recommendations Assessment, Development, and Evaluation (GRADE) was used to examine certainty of evidence.Results Data were obtained from 4 studies comprising 614 patients. The sample represented 86% of all participants ever included in double-blind placebo-controlled SSRI trials for pediatric OCD. Meta-analysis showed reduction of 3.0 CY-BOCS points compared with placebo (95% CI 2.5-3.5), corresponding to a small effect size (0.38 Hedges’ g). Analysis of response showed an odds ratio of 1.89 (95% CI 1.45-2.45). Of all possible modifiers, severity was correlated negatively with odds ratio for response (β = −0.92, p = .0074). Risk of bias was generally low. All studies were performed in North America with an overrepresentation of White participants. Findings were limited by inability to include data on additional variables such as socioeconomic status and comorbidities.Conclusion This IPD meta-analysis showed a small effect size of SSRIs in pediatric OCD, with baseline severity as a negative modifier of response. Generalizability of findings might be limited by selective inclusion of White, North American participants.Plain language summary Selective serotonin reuptake inhibitors (SSRIs) are widely used to treat children and adolescents with obsessive-compulsive disorder (OCD), but their effects have not been analyzed using individual participant data (IPD). Using data of 4 randomized, placebo-controlled trials comprising of 614 patients, this meta-analysis showed that SSRIs provided a modest improvement of 3 points on the Children’s Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) compared to placebo. Children with more severe symptoms at baseline were less likely to respond. All studies were conducted in North America, with an overrepresentation of White participants. Children with more severe symptoms at baseline were less likely to respond well. These findings confirm the efficacy of SSRIs while underscoring the need for more diverse research populations to better understand their effects in pediatric OCD.Study registration information Patient Characteristics and Efficacy of SSRI Treatment in Children and Adolescents With Obsessive Compulsive Disorder: An Individual Participant Data Meta-analysis of Randomized, Placebo-Controlled Trials; https://www.crd.york.ac.uk/PROSPERO/view/CRD42023486079 Link: ./index.php?lvl=notice_display&id=31643
in Journal of the American Academy of Child & Adolescent Psychiatry > Año 2025 - Vol. 64 - No. 7 (July) . - pp 775-785[artículo] Systematic Review and Meta-Analysis of Individual Participant Data: Randomized, Placebo-Controlled Trials of Selective Serotonin Reuptake Inhibitors for Pediatric Obsessive-Compulsive Disorder [texto impreso] . - 2026 . - pp 775-785.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of the American Academy of Child & Adolescent Psychiatry > Año 2025 - Vol. 64 - No. 7 (July) . - pp 775-785
Etiquetas: metaanálisis de datos de participantes individuales, trastorno obsesivo-compulsivo infantil, ensayos controlados aleatorios, ISRS Resumen: Objective Selective serotonin reuptake inhibitors (SSRIs) are the first choice in pharmacotherapy for children and adolescents with obsessive-compulsive disorder (OCD). SSRI trials for pediatric OCD have not been investigated using individual participant data (IPD), which is crucial for detecting patient-level effect modifiers. This study performed an IPD meta-analysis of efficacy of SSRIs compared with placebo and a meta-regression on baseline patient characteristics that might modify efficacy.Method Crude participant data from short-term, randomized, placebo-controlled SSRI trials for pediatric OCD were obtained from the registry of the Dutch regulatory authority. A systematic literature search was also performed, and authors were approached to provide IPD. A 1- and 2-stage analysis was conducted, with change on Children’s Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) as the primary outcome. Odds ratio (OR) with ≥35% CY-BOCS reduction was used as the responder outcome measure. Modifying effect of age, sex, weight, duration of illness, family history, and baseline symptom severity was examined. The Cochrane RoB 2.0 tool was used to examine methodological rigor, and Grading of Recommendations Assessment, Development, and Evaluation (GRADE) was used to examine certainty of evidence.Results Data were obtained from 4 studies comprising 614 patients. The sample represented 86% of all participants ever included in double-blind placebo-controlled SSRI trials for pediatric OCD. Meta-analysis showed reduction of 3.0 CY-BOCS points compared with placebo (95% CI 2.5-3.5), corresponding to a small effect size (0.38 Hedges’ g). Analysis of response showed an odds ratio of 1.89 (95% CI 1.45-2.45). Of all possible modifiers, severity was correlated negatively with odds ratio for response (β = −0.92, p = .0074). Risk of bias was generally low. All studies were performed in North America with an overrepresentation of White participants. Findings were limited by inability to include data on additional variables such as socioeconomic status and comorbidities.Conclusion This IPD meta-analysis showed a small effect size of SSRIs in pediatric OCD, with baseline severity as a negative modifier of response. Generalizability of findings might be limited by selective inclusion of White, North American participants.Plain language summary Selective serotonin reuptake inhibitors (SSRIs) are widely used to treat children and adolescents with obsessive-compulsive disorder (OCD), but their effects have not been analyzed using individual participant data (IPD). Using data of 4 randomized, placebo-controlled trials comprising of 614 patients, this meta-analysis showed that SSRIs provided a modest improvement of 3 points on the Children’s Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) compared to placebo. Children with more severe symptoms at baseline were less likely to respond. All studies were conducted in North America, with an overrepresentation of White participants. Children with more severe symptoms at baseline were less likely to respond well. These findings confirm the efficacy of SSRIs while underscoring the need for more diverse research populations to better understand their effects in pediatric OCD.Study registration information Patient Characteristics and Efficacy of SSRI Treatment in Children and Adolescents With Obsessive Compulsive Disorder: An Individual Participant Data Meta-analysis of Randomized, Placebo-Controlled Trials; https://www.crd.york.ac.uk/PROSPERO/view/CRD42023486079 Link: ./index.php?lvl=notice_display&id=31643 Testing the Shamiri Intervention and Its Components With Kenyan Adolescents During the COVID-19 Pandemic: Outcomes of a Universal, 5-Arm Randomized Controlled Trial en Journal of the American Academy of Child & Adolescent Psychiatry, Año 2025 - Vol. 64 - No. 7 (July)
[artículo]
Título : Testing the Shamiri Intervention and Its Components With Kenyan Adolescents During the COVID-19 Pandemic: Outcomes of a Universal, 5-Arm Randomized Controlled Trial Tipo de documento: texto impreso Fecha de publicación: 2026 Artículo en la página: pp 786-798 Idioma : Inglés (eng) Idioma original : Inglés (eng) Etiquetas: ansiedad, psicoterapia infantil y adolescente, pandemia de COVID-19, depresión, salud mental mundial
,Resumen: Objective Mental health problems are prevalent among African adolescents, but professional treatment capacity is limited. Shamiri, an efficient lay provider–delivered intervention, has significantly reduced depression and anxiety symptoms in previous randomized controlled trials (RCTs). This trial investigated effects of the full Shamiri intervention and its components (growth-only, gratitude-only, and values-only) against a study skills control.Method In a 5-group RCT with adolescents from Kenyan high schools, anxiety, depression, and well-being were self-reported through 8-month follow-up. The RCT occurred immediately after an unanticipated government-mandated COVID-19 shutdown forced 3 years of schoolwork into 2 years, escalating academic pressures.Results Participants (N = 1,252; 48.72% female) were allocated to: growth (n = 249), gratitude (n = 237), values (n = 265), Shamiri (n = 250), and study skills (n = 251) conditions. Longitudinal multilevel models showed that, across all conditions, anxiety scores significantly improved at midpoint (B = −0.847), end point (B = −2.948), 1-month (B = −1.587), 3-month (B = −2.374), and 8-month (B = −1.917) follow-ups. Depression scores also improved significantly at midpoint (B = −0.796), end point (B = −3.126), 1-month (B = −2.382), 3-month (B = −2.521), and 8-month (B = −2.237) follow-ups. Well-being scores improved significantly at midpoint (B = 1.73), end point (B = 3.44), 1-month (B = 2.21), 3-month (B = 1.78), and 8-month (B = 1.59) follow-ups. Symptom reduction with Shamiri matched that of pre–COVID-19 trials, but symptom reduction with study skills far outpaced that of trials before the COVID-19–related school shutdown (31% greater anxiety reduction and 60% greater depression reduction). Thus, in contrast to previous RCTs, this COVID-19–era trial showed no significant differences between outcomes in any intervention and active control groups.Conclusion Our RCT conducted during a post–COVID-19 period of heightened academic pressure produced unexpected results. Improvements in youth-reported anxiety and depression were consistent with previous trials for Shamiri, but markedly larger than in previous trials for study skills. Control interventions teaching life skills may produce mental health benefits when they convey skills of particular contextual relevance.Plain language summary In this large 5-group randomized controlled trial involving 1,252 Kenyan adolescents, the authors compared the Shamiri intervention to its component interventions (growth mindset, gratitude, and values affirmation) and a study-skills control. This study was conducted right after an unanticipated government-mandated COVID-19 shutdown forced 3 years of schoolwork into 2 years. Benchmarking analyses against previous trials showed approximately equal effects of Shamiri over time, but a 31% greater anxiety reduction and 60% greater depression reduction for the study-skills condition. These findings highlight the potential of teaching highly relevant study-skills for improving mental health when youth are under considerable academic pressure.Clinical trial registration Five-Arm Shamiri Trial; https://pactr.samrc.ac.za/TrialDisplay.aspx?TrialID=14677 Link: ./index.php?lvl=notice_display&id=31644
in Journal of the American Academy of Child & Adolescent Psychiatry > Año 2025 - Vol. 64 - No. 7 (July) . - pp 786-798[artículo] Testing the Shamiri Intervention and Its Components With Kenyan Adolescents During the COVID-19 Pandemic: Outcomes of a Universal, 5-Arm Randomized Controlled Trial [texto impreso] . - 2026 . - pp 786-798.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of the American Academy of Child & Adolescent Psychiatry > Año 2025 - Vol. 64 - No. 7 (July) . - pp 786-798
Etiquetas: ansiedad, psicoterapia infantil y adolescente, pandemia de COVID-19, depresión, salud mental mundial
,Resumen: Objective Mental health problems are prevalent among African adolescents, but professional treatment capacity is limited. Shamiri, an efficient lay provider–delivered intervention, has significantly reduced depression and anxiety symptoms in previous randomized controlled trials (RCTs). This trial investigated effects of the full Shamiri intervention and its components (growth-only, gratitude-only, and values-only) against a study skills control.Method In a 5-group RCT with adolescents from Kenyan high schools, anxiety, depression, and well-being were self-reported through 8-month follow-up. The RCT occurred immediately after an unanticipated government-mandated COVID-19 shutdown forced 3 years of schoolwork into 2 years, escalating academic pressures.Results Participants (N = 1,252; 48.72% female) were allocated to: growth (n = 249), gratitude (n = 237), values (n = 265), Shamiri (n = 250), and study skills (n = 251) conditions. Longitudinal multilevel models showed that, across all conditions, anxiety scores significantly improved at midpoint (B = −0.847), end point (B = −2.948), 1-month (B = −1.587), 3-month (B = −2.374), and 8-month (B = −1.917) follow-ups. Depression scores also improved significantly at midpoint (B = −0.796), end point (B = −3.126), 1-month (B = −2.382), 3-month (B = −2.521), and 8-month (B = −2.237) follow-ups. Well-being scores improved significantly at midpoint (B = 1.73), end point (B = 3.44), 1-month (B = 2.21), 3-month (B = 1.78), and 8-month (B = 1.59) follow-ups. Symptom reduction with Shamiri matched that of pre–COVID-19 trials, but symptom reduction with study skills far outpaced that of trials before the COVID-19–related school shutdown (31% greater anxiety reduction and 60% greater depression reduction). Thus, in contrast to previous RCTs, this COVID-19–era trial showed no significant differences between outcomes in any intervention and active control groups.Conclusion Our RCT conducted during a post–COVID-19 period of heightened academic pressure produced unexpected results. Improvements in youth-reported anxiety and depression were consistent with previous trials for Shamiri, but markedly larger than in previous trials for study skills. Control interventions teaching life skills may produce mental health benefits when they convey skills of particular contextual relevance.Plain language summary In this large 5-group randomized controlled trial involving 1,252 Kenyan adolescents, the authors compared the Shamiri intervention to its component interventions (growth mindset, gratitude, and values affirmation) and a study-skills control. This study was conducted right after an unanticipated government-mandated COVID-19 shutdown forced 3 years of schoolwork into 2 years. Benchmarking analyses against previous trials showed approximately equal effects of Shamiri over time, but a 31% greater anxiety reduction and 60% greater depression reduction for the study-skills condition. These findings highlight the potential of teaching highly relevant study-skills for improving mental health when youth are under considerable academic pressure.Clinical trial registration Five-Arm Shamiri Trial; https://pactr.samrc.ac.za/TrialDisplay.aspx?TrialID=14677 Link: ./index.php?lvl=notice_display&id=31644 Cross-Cultural Comparison of the Strengths and Difficulties Self-Report Questionnaire in 12 Asian and European Countries en Journal of the American Academy of Child & Adolescent Psychiatry, Año 2025 - Vol. 64 - No. 7 (July)
[artículo]
Título : Cross-Cultural Comparison of the Strengths and Difficulties Self-Report Questionnaire in 12 Asian and European Countries Tipo de documento: texto impreso Fecha de publicación: 2026 Artículo en la página: pp 799-809 Idioma : Inglés (eng) Idioma original : Inglés (eng) Etiquetas: salud mental de los adolescentes, investigación intercultural, estructura factorial, invarianza de la medición, Cuestionario de Fortalezas y Dificultades (SDQ) Resumen: Objective The self-report Strengths and Difficulties Questionnaire (SDQ) is widely used globally; hence, the validity of the intergroup comparisons is essential. This study examined the structure of the self-report SDQ in a large multinational adolescent sample, tested its measurement invariance across genders and countries, and compared youth mental health in 12 European and Asian countries.Method This study is part of the Eurasian Child Mental Health Study (EACMHS), a cross-cultural research study of child and adolescent well-being and mental health in 12 Asian and European countries. The sample (N = 26,306) came from a cross-sectional school-based survey of adolescents. Confirmatory factor analysis was used to assess a common measurement model for the self-report SDQ and the measurement invariance of the model across gender and country.Results Fit indices in the total sample, in each gender, and in each of the 12 countries separately supported the use of the first-order 3-factor model (without the reverse-coded items) as a common measurement model for the self-report SDQ. Measurement invariance analyses provided good support for configural, metric, and scalar invariance across gender; however, metric invariance across countries was not supported. There were significant gender main effects for all SDQ subscales except for hyperactivity/inattention. Culture had significant main effects and moderated the magnitude of gender differences in all subscales.Conclusion The present findings support the use of the correlated 3-factor model comprising the positive dimension of prosocial behavior and 2 broad groupings of internalizing and externalizing problems, without the reverse-coded problem items, as a common measurement model for the self-report SDQ internationally.Plain language summary Using a sample of 26,306 adolescents from 12 European and Asian countries, this study examined how well the Strengths and Difficulties Questionnaire (SDQ), a commonly used measure to assess child and adolescent mental health, can be used to compare child and adolescent mental health between different countries. In addition, the authors also measured adolescent mental health symptoms across the 12 countries. The study findings suggested that in all countries, girls scored higher than boys on prosocial behaviors and internalizing problems such as symptoms of depression and anxiety. However, the extent to which genders differed on these features varied across cultures. Link: ./index.php?lvl=notice_display&id=31645
in Journal of the American Academy of Child & Adolescent Psychiatry > Año 2025 - Vol. 64 - No. 7 (July) . - pp 799-809[artículo] Cross-Cultural Comparison of the Strengths and Difficulties Self-Report Questionnaire in 12 Asian and European Countries [texto impreso] . - 2026 . - pp 799-809.
Idioma : Inglés (eng) Idioma original : Inglés (eng)
in Journal of the American Academy of Child & Adolescent Psychiatry > Año 2025 - Vol. 64 - No. 7 (July) . - pp 799-809
Etiquetas: salud mental de los adolescentes, investigación intercultural, estructura factorial, invarianza de la medición, Cuestionario de Fortalezas y Dificultades (SDQ) Resumen: Objective The self-report Strengths and Difficulties Questionnaire (SDQ) is widely used globally; hence, the validity of the intergroup comparisons is essential. This study examined the structure of the self-report SDQ in a large multinational adolescent sample, tested its measurement invariance across genders and countries, and compared youth mental health in 12 European and Asian countries.Method This study is part of the Eurasian Child Mental Health Study (EACMHS), a cross-cultural research study of child and adolescent well-being and mental health in 12 Asian and European countries. The sample (N = 26,306) came from a cross-sectional school-based survey of adolescents. Confirmatory factor analysis was used to assess a common measurement model for the self-report SDQ and the measurement invariance of the model across gender and country.Results Fit indices in the total sample, in each gender, and in each of the 12 countries separately supported the use of the first-order 3-factor model (without the reverse-coded items) as a common measurement model for the self-report SDQ. Measurement invariance analyses provided good support for configural, metric, and scalar invariance across gender; however, metric invariance across countries was not supported. There were significant gender main effects for all SDQ subscales except for hyperactivity/inattention. Culture had significant main effects and moderated the magnitude of gender differences in all subscales.Conclusion The present findings support the use of the correlated 3-factor model comprising the positive dimension of prosocial behavior and 2 broad groupings of internalizing and externalizing problems, without the reverse-coded problem items, as a common measurement model for the self-report SDQ internationally.Plain language summary Using a sample of 26,306 adolescents from 12 European and Asian countries, this study examined how well the Strengths and Difficulties Questionnaire (SDQ), a commonly used measure to assess child and adolescent mental health, can be used to compare child and adolescent mental health between different countries. In addition, the authors also measured adolescent mental health symptoms across the 12 countries. The study findings suggested that in all countries, girls scored higher than boys on prosocial behaviors and internalizing problems such as symptoms of depression and anxiety. However, the extent to which genders differed on these features varied across cultures. Link: ./index.php?lvl=notice_display&id=31645


